Optimal thrombolytic strategies for acute myocardial infarction--bolus administration

Reperfusion Strategies for Acute Myocardial Infarction: Mechanical vs. Thrombolytic Therapy

Management of patients with acute myocardial infarction represents a great challenge to emergency physicians, a task more recently complicated by the myriad of potential treatment options available. The goal of reperfusion therapy in patients with ST segment elevation myocardial infarction (STEMI) is the safest, earliest and most complete restoration of normal (TIMI-3) flow in the infarct relat...

Thrombolytic therapy for acute myocardial infarction.

Numerous factors must be considered when determining the formulary status of thrombolytic agents for the treatment of acute myocardial infarction. Defined treatment options, predicted outcomes, and the economic consequences of this disorder continue to evolve from clinical trials. Pharmacists have a major role in delivering patient care, with responsibility for evaluating, procuring, and monito...

Systemic thrombolytic therapy of acute myocardial infarction?

Thrombolytic therapy in acute myocardial infarction Paul

Infarct size limitation has been a therapeutic aim for many years, particularly in view of the known close relationship between the extent of myocardial damage occurring at the time of the infarction, and future morbidity and mortality. It is only in the last decade, however, since the pathophysiology of myocardial infarction has been better understood, that this aim has become a clinical reali...

Thrombolytic therapy in acute myocardial infarction.

Despite major advances made over the last decade, mortality following acute myocardial infarction (MI) is still high even for patients treated with the "front-loaded" recombinant tissue-type plasminogen activator (rt-PA) regimen: 30-day mortality is 6.3%, and it is associated with fatal cerebral hemorrhage in 1.5%. Further improvement of short- and long-term prognosis can be achieved if infusio...